The Biology core is to compile a resource of expertise, resources and reagents within the GEoPD Consortium. Its objectives are to facilitate research by members of the GEoPD Consortium and to encourage multi-site collaborations.
The descriptors expertise, resources and reagents may be subdivided into sub-categories. Some examples: Expertise may include key professionals with major interests in atypical parkinsonism, neuroimaging (PET, MRI), genetics, etc. Resources might include longitudinal clinical data, high-throughput sequence or genotype information, etc. Reagents might include inducible pluripotent cell lines (iPSCs), plasmid constructs, or mouse models for genes implicated in Parkinson’s disease.
Although there will be some overlap with other cores e.g. with the Communications core on who is a current/active GEoPD member, with the Clinical core on number of patients and control subjects for whom clinical data and DNA is available, with the Bioinformatics core on genotype/sequence information etc. It will be the Biology’s core’s responsibility to create and maintain an indexed, searchable database of biologic ‘meta-data’ for the GEoPD Consortium.
Core Leaders: Matthew Farrer , Nobutaka Hattori , Jan Aasly